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Cognitive impairment risk: white matter hyperintensity progression matters

Lisa C Silbert1, Diane B Howieson, Hiroko Dodge

  • 1Layton Aging and Alzheimer's Disease Center, Department of Neurology, CR-131, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Rd., Portland, OR 97239, USA. silbertl@ohsu.edu

Neurology
|July 15, 2009
PubMed
Summary

White matter hyperintensity (WMH) progression, not baseline volume, predicts cognitive decline in older adults. Monitoring WMH changes is crucial for identifying individuals at risk of persistent cognitive impairment (PCI).

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