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Conformational changes in redox pairs of protein structures

Samuel W Fan1, Richard A George, Naomi L Haworth

  • 1Structural and Computational Biology Program, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales 2010, Australia.

Protein Science : a Publication of the Protein Society
|July 15, 2009
PubMed
Summary

Emerging evidence suggests proteins have two disulfide subproteomes: structural and redox-active. This study found proteins in alternate redox states exhibit conformational changes, indicating physiological relevance for redox-active disulfides.

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