Related Experiment Video
Updated: Jun 21, 2026

An In Vivo Mouse Model of Total Intravenous Anesthesia During Cancer Resection Surgery
Published on: June 8, 2021
Intravenous narcotic antagonists in ambulatory oral surgery
Abstract:
Results of a study indicate that significant respiratory depression can be produced by the intravenous administration of narcotics in the anesthetic management of oral surgery patients. Naloxone hydrochloride reversed this reaction in all instances. Naloxone is a unique narcotic antagonist in that it does not possess agonistic properties of its own, it is effective in reversing respiratory depression resulting from all commonly used narcotics and narcotic antagonists, it causes no undesirable side effects, and it acts as a placebo when administered to a patient who has not had a narcotic. The use of naloxone should be considered when a potent narcotic is administered to an ambulatory patient.
Related Concept Videos
Parenteral Anesthetics: Overview
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...