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Staphylococcus lugdunensis.

K F Barker1, J C O'Driscoll, A Bhargava

  • 1Public Health Laboratory, St George's Hospital, London.

Journal of Clinical Pathology
|October 1, 1991
PubMed
Summary
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Penicillin-resistant Staphylococcus lugdunensis caused fatal endocarditis. This rare bacterium was not found in 978 coagulase-negative staphylococcal isolates, highlighting ornithine decarboxylase as the key identification method.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Staphylococcus lugdunensis is a coagulase-negative staphylococcal species.
  • Endocarditis is a serious infection of the heart valves.
  • Rheumatic heart disease can predispose individuals to valve damage and subsequent infections.

Observation:

  • A fatal case of endocarditis caused by penicillin-resistant Staphylococcus lugdunensis on a rheumatic heart disease-damaged native valve is presented.
  • A retrospective analysis of 978 coagulase-negative staphylococcal blood culture isolates was conducted.
  • Staphylococcus lugdunensis was not identified in any of the 978 isolates examined.

Findings:

  • Penicillin resistance in Staphylococcus lugdunensis poses a significant clinical challenge.

Related Experiment Videos

  • The isolation frequency of Staphylococcus lugdunensis from blood cultures appears to be low.
  • Ornithine decarboxylase production is identified as the sole reliable method for accurate Staphylococcus lugdunensis identification.
  • Implications:

    • Accurate and rapid identification of Staphylococcus lugdunensis is crucial for effective treatment of endocarditis.
    • Clinicians should consider Staphylococcus lugdunensis in cases of endocarditis, especially with resistant strains.
    • Further research into the prevalence and diagnostic methods for Staphylococcus lugdunensis is warranted.