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Related Experiment Videos

Marking of resection margins.

C Hunter-Craig1, B Lee-McDonagh, H G Penman

  • 1Department of Histopathology, Crawley Hospital.

Journal of Clinical Pathology
|October 1, 1991
PubMed
Summary

Starch powder effectively marks breast tissue resection margins in surgical specimens. This quick, clean, and cost-effective method aids microscopic margin assessment but is unsuitable for irregular specimens.

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Area of Science:

  • Surgical Pathology
  • Histotechnology

Background:

  • Accurate marking of surgical resection margins is crucial for evaluating tumor-free tissue in breast cancer surgery.
  • Traditional margin marking techniques can be time-consuming, costly, or interfere with subsequent analysis.

Purpose of the Study:

  • To evaluate the efficacy of starch powder as a simple, inexpensive marker for breast tissue resection margins.

Main Methods:

  • Formalin-fixed breast tissue specimens were rolled in starch powder (e.g., glove powder) to mark the surgically cut surface.
  • The adherence and visibility of starch were assessed microscopically using crossed polarizers.
  • Potential interference with radiology of specimens or tissue blocks was evaluated.

Main Results:

  • Starch powder adhered well to the breast tissue specimens.
  • Starch particles were clearly visible microscopically when using crossed polarizers.
  • Minimal 'carry-over' of starch to adjacent tissues was observed, and radiological assessment was not compromised.

Conclusions:

  • Starch powder is a suitable, practical, and economical single marker for surgically cut surfaces of most breast tissue specimens.
  • The method is quick, clean, and does not interfere with radiological evaluations.
  • This technique should not be used for ragged or disrupted specimens where accurate margin delineation is compromised.

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