Related Experiment Video

Updated: Jun 21, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Acute myocardial infarction with myocardial perfusion defect detected by contrast-enhanced computed tomography

Tetsuo Ichinose1, Miki Yamase, Yuki Yokomatsu

  • 1Department of Cardiology, Juntendo University Urayasu Hospital, Urayasu. tichinose@juntendo-urayasu.jp

Internal Medicine (Tokyo, Japan)
|July 16, 2009
PubMed

Insights

Contrast-enhanced CT effectively diagnosed acute myocardial infarction (AMI) in two patients presenting with chest pain and cardiac tamponade. This imaging technique identified myocardial defects before coronary angiography, aiding early AMI diagnosis.

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Acute myocardial infarction (AMI) and acute aortic dissection can present with similar symptoms.
  • Early and accurate diagnosis is crucial for effective patient management.

Observation:

  • Two patients presented with distinct cardiac emergencies: one with migratory chest pain, the other with cardiac tamponade.
  • Contrast-enhanced computed tomography (CE-CT) revealed a low-density area in the left ventricular postero-lateral wall in both cases.

Findings:

  • CE-CT identified early contrast defects indicative of reduced myocardial blood flow, consistent with AMI.
  • Coronary angiograms confirmed lesions in the left circumflex artery in these cases.
  • CE-CT facilitated the diagnosis of AMI prior to coronary angiography.

Implications:

  • CE-CT serves as a valuable tool for the early diagnosis of AMI.
  • This imaging modality can help differentiate AMI from other acute cardiac conditions.
  • Integrating CE-CT into diagnostic workflows can improve patient outcomes through timely intervention.

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