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Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

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Published on: March 4, 2016

Delayed skin grafting utilizing autologous banked tissue.

Samir Mardini¹, Francisco J Agullo, Christopher J Salgado

¹Division of Plastic Surgery, Mayo Clinic, Rochester, MN 55905, USA. mardinis@aol.com

Annals of Plastic Surgery

|July 16, 2009

Summary

This study presents a reliable bedside skin graft technique for voice reconstruction patients. Skin grafts harvested during surgery and temporarily stored at the donor site showed over 95% success, avoiding complications.

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Area of Science:

Plastic Surgery
Regenerative Medicine
Otolaryngology

Background:

Delayed skin grafting is common in voice reconstruction using bowel flaps to manage swelling and monitor the site.
Traditional skin banking methods may face regulatory challenges or be impractical in certain clinical scenarios.

Purpose of the Study:

To evaluate a novel bedside technique for harvesting and temporarily storing skin grafts for voice reconstruction.
To assess the efficacy and safety of this skin graft banking method.

Main Methods:

Skin grafts were harvested from the thigh during intestinal transfer in ten patients.
Grafts were banked at the donor site and transferred to the recipient site between postoperative days 3 and 8 under sedation.
Graft take and healing were monitored, with follow-up ranging from 5 to 12 months.

Main Results:

The bedside skin graft transfer technique was well-tolerated by all patients.
Graft take exceeded 95% in all cases, with no related complications.
All banked skin grafts demonstrated complete healing at follow-up.

Conclusions:

Bedside skin graft banking is a reliable and effective method for voice reconstruction.
This technique offers a viable alternative when traditional skin banking is not feasible due to regulations or clinical constraints.
The method ensures high graft take and successful healing with minimal complications.