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Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases
Published on: August 27, 2021
Mirror image phage display--a method to generate D-peptide ligands for use in diagnostic or therapeutical
Susanne Aileen Funke1, Dieter Willbold
1Forschungszentrum Jülich, ISB-3, Jülich, Germany.
Molecular Biosystems
|July 16, 2009
Abstract:
Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.
