Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanisms of Membrane-bending01:15

Mechanisms of Membrane-bending

The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by specific lipids and proteins. The membrane bending can be transient as seen in vesicles or stable for a long time as in microvilli. Cells regulate the size, location, and duration of the membrane curvature.
Membrane bending can happen due to intrinsic changes in lipid composition or extrinsic association with different proteins. The proteins involved...
Introduction to Membrane Traffic01:44

Introduction to Membrane Traffic

The ER, Golgi apparatus, endosomes, and lysosomes work in tandem to modify, sort, and package proteins and lipids. An integrated membrane trafficking network facilitates the back and forth shuttling of molecules within different organelles in the same cell or across the cell membrane.
The transport of soluble and membrane proteins is mediated by transport vesicles that collect cargo from one cellular compartment and deliver it to another by fusing with the target organelle membrane. The Rab...
Mechanisms of Membrane Domain Formation00:59

Mechanisms of Membrane Domain Formation

Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
Another mechanism for membrane domain formation involves membrane proteins interacting with cytoskeletal...
Fluid Mosaic Model01:19

Fluid Mosaic Model

Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich with the analogy of...
Membrane Domains01:18

Membrane Domains

The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other critical cellular processes. These domains can differ in size, composition, function, and lifespan.
Protein Domains
The membrane comprises a group of distinct proteins responsible for carrying out a cell's specific function. For example, the plasma membrane of the human sperm, or a single germ cell, contains a unique set of proteins in the anterior...
Protein Diffusion in the Membrane01:24

Protein Diffusion in the Membrane

Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photo-Rechargeable Organic Supercapacitor via Light-Activated Electrolytes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Chiral Amine-Induced Assembly of Toroidal Structures with a Carboxylic Acid-Functionalized, Polymerizable Macrocyclic Diacetylene.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Similar but Distinct-Biochemical Characterization of the  Staphylococcus aureus Serine Hydrolases FphH and FphI.

Proteins·2024
Same author

Resilient sustainable current and emerging technologies for foodborne pathogen detection.

Sustainable food technology·2024
Same author

Physics and chemistry of nitrogen dioxide (NO<sub>2</sub>) adsorption on gallium nitride (GaN) surface and its interaction with the yellow-luminescence-associated surface state.

Journal of colloid and interface science·2024
Same author

A Matter of Charge: Electrostatically Tuned Coassembly of Amphiphilic Peptides.

Small (Weinheim an der Bergstrasse, Germany)·2024

Related Experiment Video

Updated: Jun 21, 2026

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies
07:31

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies

Published on: September 1, 2023

Biomimetic approaches for studying membrane processes.

Raz Jelinek1, Liron Silbert

  • 1Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel. razj@bgu.ac.il

Molecular Biosystems
|July 16, 2009
PubMed
Summary
This summary is machine-generated.

This review explores innovative biomimetic systems for studying membrane processes and biomolecular interactions. It highlights novel concepts for analyzing complex biological questions at the chemistry/biology interface.

More Related Videos

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
10:31

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Published on: September 2, 2020

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions
12:18

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Related Experiment Videos

Last Updated: Jun 21, 2026

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies
07:31

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies

Published on: September 1, 2023

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
10:31

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Published on: September 2, 2020

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions
12:18

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Area of Science:

  • Biomaterials Science
  • Biochemistry
  • Analytical Chemistry

Background:

  • Membrane processes are crucial in biological systems.
  • Understanding biomolecular interactions with membranes is key to deciphering cellular functions.
  • Existing analytical methods may not fully capture the complexity of membrane dynamics.

Purpose of the Study:

  • To review recent innovative systems and experimental approaches for investigating membrane processes.
  • To emphasize the role of biomimetics in addressing complex biological questions.
  • To highlight novel concepts for the analysis of membrane processes beyond traditional sensors and assays.

Main Methods:

  • Focus on biomimetic systems and experimental strategies.
  • Review of interdisciplinary approaches at the chemistry/biology interface.
  • Analysis of innovative concepts for studying membrane phenomena.

Main Results:

  • Identification of emerging trends in membrane process investigation.
  • Showcasing the utility of biomimetic approaches.
  • Highlighting advancements in analytical concepts for membrane studies.

Conclusions:

  • Biomimetic strategies offer powerful tools for understanding membrane-associated biological questions.
  • Innovative experimental systems are advancing the analysis of membrane processes.
  • The chemistry/biology interface is critical for developing next-generation membrane analysis techniques.