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Bacterial Meningitis I: Introduction

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Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

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Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

[Enterococcal meningitis in adults].

P Laguna Del Estal¹, C García Zubiri, R García Madero

¹Servicio de Medicina Interna, Hospital Universitario Puerta de Hierro, Madrid. pdl02m@saludalia.com

Neurologia (Barcelona, Spain)

|July 16, 2009

Summary

This summary is machine-generated.

Enterococcal meningitis (EM) is rare, often occurring after surgery, particularly in patients with cerebrospinal fluid (CSF) devices. This study found no deaths or lasting effects in six adult cases, suggesting a favorable outcome with treatment.

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Published on: October 29, 2014

Area of Science:

Infectious Diseases
Neurology
Microbiology

Context:

Enterococcus species are increasingly recognized as significant pathogens.
Enterococcal meningitis (EM) is an infrequent but serious infection.
Understanding EM's clinical features and outcomes is crucial for patient management.

Purpose:

To describe the clinical characteristics and outcomes of adult patients with enterococcal meningitis (EM).
To identify predisposing factors and common clinical presentations of EM.
To evaluate treatment strategies and patient prognosis in EM.

Summary:

This study reviewed six adult cases of EM diagnosed over 25 years at a tertiary hospital.
All cases were postoperative, with cerebrospinal fluid (CSF) devices being the most common predisposing factor.
Patients presented with acute symptoms; treatment involved vancomycin or ampicillin/gentamicin, with CSF device removal, leading to no deaths or sequelae.

Impact:

Highlights the importance of considering EM in postoperative patients with meningitis, especially those with CSF devices.
Demonstrates that EM, despite its severity, can have a favorable prognosis with appropriate management.
Provides valuable data on the clinical course and outcomes of this rare infection.