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Updated: Jun 21, 2026

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation
Published on: August 19, 2020
Perivascular epithelioid cell neoplasms: pathology and pathogenesis
Andrew L Folpe1, David J Kwiatkowski
1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. folpe.andrew@mayo.edu
Perivascular epithelioid cell neoplasms are rare tumors. This review covers their clinical, pathologic, immunohistochemical, and genetic features for a comprehensive understanding.
Area of Science:
- Oncology
- Pathology
- Genetics
Background:
- Perivascular epithelioid cell (PEC) neoplasms represent a rare and distinct group of tumors.
- These neoplasms are characterized by specific morphologic and immunophenotypic features.
Purpose of the Study:
- To provide a comprehensive summary of current knowledge regarding PEC neoplasms.
- To consolidate information on the clinical, pathologic, immunohistochemical, and genetic aspects of these rare tumors.
Main Methods:
- This study is a review article.
- It synthesizes existing literature and data on PEC neoplasms.
Main Results:
- The review details the multifaceted characteristics of PEC neoplasms.
- It highlights the importance of integrated diagnostic criteria.
Conclusions:
- A thorough understanding of PEC neoplasms requires integrating clinical, pathologic, immunohistochemical, and genetic data.
- Further research may elucidate more about the pathogenesis and optimal management of these rare neoplasms.
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