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Updated: Jun 21, 2026

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
Published on: August 10, 2012
Dopamine-beta-hydroxylase activity in normal and sympathectomized carotid bodies
E Morgado1, F Llados, P Zapata
1Department of Neurobiology, Catholic University of Chile, Santiago, Chile.
Abstract:
Normal carotid bodies excised from cats showed DBH values of 5.04 + or - 0.53 nmol [(3)H]octopamine formed/h/100 mg tissue (x + or - S.E. ). Values from sympathectomized carotid bodies were not significantly different. While the ganglio-glomerular nerves, providing the sympathetic innervation of the carotid bifurcation, had a high DBH level, this was low in the carotid sinus nerve, providing its sensory innervation. Glomeral DBH may be contained in a special type of noradrenergic glomus cells, distinct from the most common dopaminergic glomus cells.
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