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Olfactory Assays for Mouse Models of Neurodegenerative Disease
Published on: August 25, 2014
Specific anosmia to geraniol in mice
1Department of Physiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Va. 23298 U.S.A.
Neuroscience Letters
|July 17, 2009
Abstract:
The ability of Swiss mice to detect geraniol, menthol, benzaldehyde, and salicylaldehyde was tested by an active avoidance paradigm. Fourteen animals with specific anosmia to geraniol were obtained. Of these, seven were also unable to detect phenylethyl alcohol. Both compounds have similar odor quality in humans and are believed to stimulate the same receptors. The data on the specifically anosmic mice suggest that these structurally dissimilar compounds are detected by the same receptors in mice.

