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Updated: Jun 21, 2026

Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology
Published on: June 25, 2014
Does the skin tell the somatosensory cortex how to construct a map of the periphery?
1Institute of Anatomy, University of Lausanne, 9 rue du Bugnon, 1011 Lausanne, Switzerland.
Abstract:
When the muzzle of a mouse bears an occasional extra whisker, the corresponding barrelfield (in the contralateral somatosensory cortex) contains an extra barrel in a topologically equivalent place and vice versa. Since the pattern of vibrissal follicles is laid down 7 days before birth and that of the barrels 3 days after birth, the former pattern appears to be responsible for the establishment of the latter. We propose that the answer to the title's question is yes.
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