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Updated: Jun 21, 2026
Generating Retinal Injury Models in Xenopus Tadpoles
Published on: October 13, 2023
Aberrant ipsilateral retinotectal projection following optic nerve section in Xenopus
1Department of Human Morphology, School of Medicine, The Flinders University of South Australia, South Australia 50422, Australia.
Abstract:
Optic fibre regeneration in young Xenopus was studied by [(3)H]proline autoradiography and by mapping the visuotectal projection electrophysiologically from 5 to 210 days after sectioning the right optic nerve. Regenerated optic fibers were demonstrated morphologically both in the contra and ipsilateral tecta. In contrast, electrophysiological studies showed that the visuotectal projection was detectable only in the contralateral tectum. The apparent disparity between morphological and electrophysiological results is discussed.