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Updated: Jun 21, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

Factor V Leiden: impact on infusion nursing practice.

Sharon M Weinstein¹

¹Core Consulting Group, Hawthorn Woods, Illinois 60047, USA. sharonw@corelimited.com

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society

|July 17, 2009

Summary

Factor V Leiden, a common genetic blood-clotting disorder, is routinely screened in pregnant women and at-risk individuals. This article details its genetics, occurrence, treatment, and clinical practice implications for better patient outcomes.

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Last Updated: Jun 21, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

Area of Science:

Medical Genetics
Hematology
Clinical Practice

Background:

Factor V Leiden is a common inherited thrombophilia.
Personal and clinical experience highlights its significant impact on patient care.
Genetic screening is increasingly routine in specific populations.

Purpose of the Study:

To provide a comprehensive overview of factor V Leiden.
To discuss the implications of genetic screening for factor V Leiden in clinical practice.
To inform healthcare providers about the genetics, occurrence, and treatment of factor V Leiden.

Main Methods:

Literature review on factor V Leiden genetics and epidemiology.
Analysis of current clinical guidelines for screening and testing.
Discussion of treatment strategies and practice management.

Main Results:

Factor V Leiden is a prevalent genetic mutation affecting blood coagulation.
Screening is common in pregnant women and pre-operative patients at risk.
Management involves understanding genetic risk, treatment options, and preventative measures.

Conclusions:

Factor V Leiden requires informed clinical management due to its prevalence and potential complications.
Genetic screening plays a crucial role in identifying at-risk individuals.
Understanding this condition is vital for optimizing patient care and outcomes.