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Updated: Jun 21, 2026
06:40
An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice
Published on: March 19, 2018
Epidural cerebrospinal fluid collection after lumbar puncture
Paul L Aronson1, Mark R Zonfrillo
1Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. aronsonp@email.chop.edu
Pediatric Emergency Care
|July 17, 2009
Summary
A cerebrospinal fluid (CSF) leak after lumbar puncture can cause headaches and backaches. These CSF collections are typically managed nonoperatively, preventing long-term neurological issues.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Lumbar puncture is a frequent emergency department procedure.
- Cerebrospinal fluid (CSF) leaks can arise from dural tears post-procedure.
Observation:
- A patient developed a symptomatic epidural CSF collection following a diagnostic lumbar puncture.
- Such collections can manifest with transient side effects like headache and backache, or more severe symptoms.
Findings:
- CSF collections resulting from lumbar puncture can be managed nonoperatively.
- Nonoperative management generally leads to resolution without permanent neurologic deficits.
Implications:
- This case highlights the importance of recognizing and managing symptomatic CSF collections.
- Understanding techniques to minimize CSF leak is crucial for reducing post-procedural complications.
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