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[Perspectives in inflammatory bowel diseases treatment]

Lukasz Jalocha1, Stanisław Wojtuń, Przemyslaw Dyrla

  • 1Military Institute of Health Services in Warsaw, Department of Gastroenterology, Central Clinical Hospital of the Ministry of National Defense. ljalocha@yahoo.com

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|July 18, 2009
PubMed

Development in immunology and better understanding of prolonged inflammatory process is basic in inflammatory bowel diseases treatment development. The new generation of drugs could be included infliximab and adalimumab. To the same group we include tumour necrosis factor inhibitors (infliximab, adalimumab, etanercept, certolizumab, onercept), selective adhesive molecules inhibitors (natalizumab, alicaforsen), Th1 dependent reaction inhibitors (anti-il-12, tacrolismus, il-10), lymphocytes migration inhibitors (natalizumab). Those drug are under development or in various clinical trials phases and are the future of inflammatory bowel diseases treatment.

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