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Updated: Jun 21, 2026
09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Acute renal failure in a man with a small farm
Ricardo Cestero-Rivera1, José Ramírez-Rivera, Francisco Jaume-Anselmi
1La Concepción Hospital, Puerto Rico.
Boletin De La Asociacion Medica De Puerto Rico
|July 18, 2009
Summary
Leptospirosis, a zoonotic disease, can cause severe symptoms like jaundice and acute renal failure. Early diagnosis and treatment with antibiotics are crucial for recovery, especially in regions with high incidence.
Area of Science:
- Infectious Diseases
- Zoonotic Diseases
- Microbiology
Background:
- Leptospirosis is a zoonotic disease caused by Leptospira spirochetes, presenting with diverse symptoms including fever, jaundice, acute renal failure, and thrombocytopenia.
- It is endemic in tropical regions, where it can be a significant cause of acute renal failure.
Observation:
- A patient with a history of owning a farm and consuming unwashed fruits presented with symptoms suggestive of leptospirosis.
- The patient's clinical presentation included fever, jaundice, acute renal failure, and thrombocytopenia, mimicking other febrile illnesses.
Findings:
- Treatment with ampicillin and hemodialysis led to marked improvement in renal function.
- Leptospira titers confirmed the diagnosis, normalizing after medical treatment.
Implications:
- Leptospirosis is an underdiagnosed and misdiagnosed disease, particularly in areas like Puerto Rico where symptoms overlap with dengue.
- Increased awareness and diagnostic vigilance are necessary for prompt identification and management of leptospirosis, especially in endemic zones.
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