Related Experiment Video
Updated: Jun 21, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
Published on: September 26, 2019
Non-Hodgkin's lymphoma presenting as ulcerative colitis
Lilliam M García Ortiz1, Francisco Jaume Anselmi, José Ramírez Rivera
1La Concepción Hospital, P.O. Box 285, San German, Puerto Rico.
A Burkitt-like lymphoma was misdiagnosed as ulcerative colitis for nine months. This aggressive malignancy requires prompt diagnosis, highlighting the need to suspect other pathologies when symptoms persist.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- High-grade Non-Hodgkin's lymphomas are aggressive hematologic malignancies.
- Differential diagnosis in persistent gastrointestinal symptoms is crucial.
- Ulcerative colitis and lymphoma can present with overlapping symptoms.
Observation:
- A case of Burkitt-like lymphoma initially treated as ulcerative colitis for nine months.
- Patient presented with significant weight loss, diarrhea, and dyspareunia.
- Symptoms persisted despite presumed ulcerative colitis treatment.
Findings:
- The persistent symptoms and rapid mass growth suggested a malignant process.
- Rectal induration indicated a pathology beyond superficial mucosal involvement.
- Histopathological examination confirmed Burkitt-like lymphoma.
Implications:
- Misdiagnosis of aggressive lymphoma can lead to delayed treatment and poorer outcomes.
- Clinical vigilance is essential to differentiate lymphoma from inflammatory bowel disease.
- Early recognition of malignancy signs is critical for effective lymphoma management.
Related Concept Videos
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease