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Effects of variations in serum estradiol concentrations on secretory endometrial development and function in

Jeremy M Groll1, Rebecca S Usadi, Bruce A Lessey

  • 1Division of Reproductive Endocrinology and Infertility, Wright-Patterson AFB, Ohio 45433, USA. Jeremy.Groll@wpafb.af.mil

Fertility and Sterility
|July 18, 2009
PubMed

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The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
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The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
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