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Updated: Jun 21, 2026

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat
Published on: October 6, 2018
[How can the number of liver transplantations be increased?]
Constantino Fondevila1, Santos Jiménez-Galanes, Juan Carlos García-Valdecasas
1Unidad de Cirugía Hepática y Trasplante, Hospital Clínic i Provincial, IMDM, CIBEREHD, Universidad de Barcelona, Barcelona, España. cfonde@clinic.ub.es
Abstract:
The number of patients suitable for liver transplantation is progressively increasing due to the excellent results achieved with this procedure, giving rise to a growing imbalance in the number of candidates on the waiting list and the number of donors. This situation has prompted transplant teams to search for alternatives to increase the number of liver grafts. On the one hand, the criteria for donation have been broadened to include donors with advanced age, liver steatosis, hepatitis B and C viruses, neoplasms, and benign underlying diseases. On the other hand, new transplant techniques have been used with grafts from split livers, living donors, sequential or domino transplants and non-heart-beating donors. Other options such as xenotransplantation and hepatocyte transplants currently lack clinical applicability.
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