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Related Experiment Video

Updated: Jun 21, 2026

High-Resolution Three-Dimensional Whole-Organ Tomography of Microbial Infections

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Published on: March 1, 2024

Paracoccidioidomycosis: high-resolution computed tomography-pathologic correlation.

Edson Marchiori¹, Paulo Marcos Valiante, Claudia Mauro Mano

¹Fluminense Federal University, Rio de Janeiro, Brazil. edmarchiori@gmail.com

European Journal of Radiology

|July 18, 2009

Summary

High-resolution computed tomography (HRCT) reveals diverse patterns in pulmonary paracoccidioidomycosis, correlating with inflammation and fibrosis. These HRCT findings aid in understanding the pathology of this fungal infection.

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Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

Published on: January 22, 2013

Area of Science:

Pulmonology
Radiology
Infectious Diseases

Background:

Pulmonary paracoccidioidomycosis is a significant fungal infection in endemic areas.
Accurate diagnosis relies on integrating imaging and pathological findings.

Purpose of the Study:

To characterize high-resolution computed tomography (HRCT) features of pulmonary paracoccidioidomycosis.
To correlate HRCT findings with histopathological results.

Main Methods:

Retrospective analysis of HRCT scans from 23 adult patients.
Consensus review of HRCT images by two chest radiologists.
Correlation of imaging findings with pathological specimens.

Main Results:

Predominant HRCT findings: ground-glass opacities, nodules, septal thickening, consolidation, cavitation, fibrosis.
Pathological features: inflammatory infiltration, granulomas, exudate, necrosis, fibrosis.
HRCT patterns reflect interstitial and airspace involvement.

Conclusions:

Pulmonary paracoccidioidomycosis exhibits varied tomography patterns.
HRCT findings are pathologically linked to inflammation, granulomatous reactions, and fibrosis.
HRCT is valuable for diagnosing and understanding pulmonary paracoccidioidomycosis.