Good syndrome accompanied by pure red cell aplasia

Thymomas are often associated with various autoimmune disorders. We herein report a middle-aged female patient with thymoma and hypogammaglobulinemia (Good syndrome) who developed symptomatic normocytic anemia. Her computed tomography (CT) scans showed a cervico-mediastinal mass. The findings of a bone marrow biopsy suggested pure red cell aplasia (PRCA), and the serum levels of all immunoglobulins were extremely low. After the resection of the tumor, which was diagnosed to be Masaoka stage II and type AB thymoma, the normocytic anemia dramatically improved, but the hypogammaglobulinemia did not recover.