Multiple fusiform cerebral aneurysms and highly elevated serum interleukin-6 in cardiac myxoma

Young-Ho Koo1, Tae-Gon Kim, Ok-Joon Kim

  • 1Department of Neurology, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam, Korea.

Insights

Cardiac myxoma (CM) can cause cerebral infarction. This rare case highlights multiple cerebral aneurysms in a CM patient, potentially linked to elevated interleukin-6 levels.

Area of Science:

  • Neurology
  • Cardiology
  • Oncology

Background:

  • Cardiac myxoma (CM) is a primary cardiac tumor.
  • Cerebral embolic infarction is a common neurologic complication of CM.
  • Cerebral aneurysms are a rare complication of CM.

Observation:

  • A 64-year-old woman presented with acute cerebral infarction and multiple, distal, fusiform cerebral aneurysms.
  • The patient had a confirmed cardiac myxoma.
  • Serum interleukin-6 (IL-6) levels were significantly elevated.

Findings:

  • Surgical resection of the cardiac myxoma led to normalization of IL-6 levels.
  • No regression of cerebral aneurysms was observed on follow-up neuroimaging.
  • This case suggests a potential association between high IL-6 and cerebral aneurysm formation in CM.

Implications:

  • Multiple cerebral aneurysms are a rare but serious complication of cardiac myxoma.
  • Elevated IL-6 may indicate an increased risk for developing cerebral aneurysms in CM patients.
  • Further research is needed to elucidate the relationship between IL-6 and aneurysmogenesis in cardiac myxoma.

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