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Published on: June 11, 2019
Multiple fusiform cerebral aneurysms and highly elevated serum interleukin-6 in cardiac myxoma
Young-Ho Koo1, Tae-Gon Kim, Ok-Joon Kim
1Department of Neurology, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam, Korea.
Insights
Cardiac myxoma (CM) can cause cerebral infarction. This rare case highlights multiple cerebral aneurysms in a CM patient, potentially linked to elevated interleukin-6 levels.
Area of Science:
- Neurology
- Cardiology
- Oncology
Background:
- Cardiac myxoma (CM) is a primary cardiac tumor.
- Cerebral embolic infarction is a common neurologic complication of CM.
- Cerebral aneurysms are a rare complication of CM.
Observation:
- A 64-year-old woman presented with acute cerebral infarction and multiple, distal, fusiform cerebral aneurysms.
- The patient had a confirmed cardiac myxoma.
- Serum interleukin-6 (IL-6) levels were significantly elevated.
Findings:
- Surgical resection of the cardiac myxoma led to normalization of IL-6 levels.
- No regression of cerebral aneurysms was observed on follow-up neuroimaging.
- This case suggests a potential association between high IL-6 and cerebral aneurysm formation in CM.
Implications:
- Multiple cerebral aneurysms are a rare but serious complication of cardiac myxoma.
- Elevated IL-6 may indicate an increased risk for developing cerebral aneurysms in CM patients.
- Further research is needed to elucidate the relationship between IL-6 and aneurysmogenesis in cardiac myxoma.
Abstract:
Cerebral embolic infarction is the most common neurologic complication of cardiac myxoma (CM). Development of cerebral aneurysms in CM is very rare. We present a 64-year-old woman with acute cerebral infarction and multiple cerebral aneurysms complicated by CM. The aneurysms were multiple, fusiform-shaped, and located in distal branch of major cerebral arteries. The serum interleukin (IL)-6 was highly elevated, which was normalized after surgical resection of CM. There was no regression of aneurysms on follow-up neuroimaging. Multiple cerebral aneurysms in CM are rare condition. Highly elevated serum IL-6 may be associated with increased risk of cerebral aneurysmal formation.
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