Related Experiment Video
Updated: Jun 21, 2026

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
Published on: May 10, 2024
Topical negative pressure in managing severe peritonitis: a positive contribution?
Amin Ibrahim Amin1, Irshad A Shaikh
1Department of Surgery, Queen Margaret Hospital, Dunfermline, Fife, Scotland KY12 0SU, United Kingdom. ibrahim.amin@faht.scot.nhs.uk
Topical negative pressure (TNP) is a safe and effective method for managing severe peritonitis, leading to successful abdominal closure in most patients. This approach shows promise for complex abdominal cases.
Area of Science:
- Surgical innovation
- Critical care medicine
Background:
- Severe peritonitis presents significant management challenges.
- Traditional methods may have limitations in complex cases.
Purpose of the Study:
- To evaluate the efficacy and safety of topical negative pressure (TNP) in managing severe peritonitis.
- To assess outcomes in patients undergoing laparotomy for peritonitis treated with TNP.
Main Methods:
- Prospective analysis of 20 patients with severe peritonitis treated with TNP.
- Utilized the VAC(R) Abdominal Dressing System and VAC GranuFoam.
- Dressing changes every 2-3 days.
Main Results:
- Successful abdominal closure achieved in 15/20 patients within 4.53 days.
- One patient required relaparotomy; two developed intestinal fistulae.
- All 20 patients survived, with some requiring later reconstruction.
Conclusions:
- Topical negative pressure (TNP) is a safe therapeutic option for severe peritonitis.
- Further research is warranted to establish TNP's definitive role in complex abdominal conditions.
Related Concept Videos
Pericarditis III: Medical Management
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.