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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 30, 2011
Performance testing of a dedicated magnetic resonance peripheral blood flow scanner
J M Kofler1, R L Morin, C M Johnson
1Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, Minnesota 55905.
Abstract:
This work presents a novel investigation of an NMR device to measure blood flow. Continuous-wave magnetic resonance scanners are now available for noninvasive peripheral blood flow measurements. The appearance of dedicated peripheral blood flow scanners in the clinical setting requires analysis of system performance. No reports were found that explore methods or results of clinical MR blood flow scanner performance evaluation. This work was undertaken to identify the testing procedures and characteristics of a clinical, dedicated NMR blood flow scanner. The dependence of flow measurement on tubing size, material, offset from isocenter, and angulation was examined. In addition, the precision and accuracy of the scanner were investigated. The results demonstrate a strong dependence between the measured blood flow and both the tube size and flow rate. The tube offset results exhibited a region of weak dependence in the center of the bore, which becomes stronger near the edge. The measured flow rate was found to be relatively insensitive to tube angles less than 30 degrees to 55 degrees. The repeatability was typically better than 5% and the table positioning was found to be highly accurate.
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