Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Activities in cellular signalling pathways: a two-edged sword?

M P Mattson1

  • 1Sanders-Brown Research Center on Aging, University of Kentucky Medical Center, Lexington 40536.

Neurobiology of Aging
|July 1, 1991
PubMed
Summary
This summary is machine-generated.

Signal transduction systems are vital for neural circuitry maintenance and plasticity. Aberrant activity in these systems can harm neurons and contribute to neurological disorders like Alzheimer

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.

Journal of molecular neuroscience : MN·2019
Same author

Nutrition and the biology of human ageing: cognitive decline/food intake and caloric restriction.

The journal of nutrition, health & aging·2013
Same author

Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse models.

Translational psychiatry·2013
Same author

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.

Cell death & disease·2013
Same author

Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan.

Neuroscience·2012
Same author

Curcumin requires tumor necrosis factor α signaling to alleviate cognitive impairment elicited by lipopolysaccharide.

Neuro-Signals·2012
Same journal

Amygdala and hippocampal volumes as neural correlates of resilience and loneliness in older adults.

Neurobiology of aging·2026
Same journal

Hippocampal-cortical structural networks in the progression of cognitive impairment: A source-based morphometry analysis in individuals with subjective cognitive decline, mild cognitive impairment and Alzheimer's disease.

Neurobiology of aging·2026
Same journal

Brain structure in the cingulate cortex and locus coeruleus in late life is associated with engagement in complex mental activities across the life span.

Neurobiology of aging·2026
Same journal

Age-related differences in motor learning, sensorimotor neurochemistry, and cortical reactivity co-occur but are dissociated.

Neurobiology of aging·2026
Same journal

How cognition and hearing-related measures covary with hippocampal subfield features from structural MRI in younger and older adults.

Neurobiology of aging·2026
Same journal

Decreased awareness of cognitive decline is associated with multimodal Alzheimer's disease biomarkers in cognitively unimpaired individuals.

Neurobiology of aging·2026
See all related articles

Area of Science:

  • Neuroscience
  • Cell Biology
  • Signal Transduction

Background:

  • Neural circuitry requires coordinated signal transduction for maintenance and plasticity.
  • Aberrant signaling can lead to neuronal damage and neurodegenerative diseases, such as Alzheimer's disease.