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Updated: Jun 21, 2026
08:56
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
[Patient with hypertransaminasemia and mononeuritis multiplex]
Rubén Díez1, Mónica Sierra, Gabriela Rascarachi
1Sección de Aparato Digestivo, Complejo Asistencial de León, León, España. rudiro@msn.com
Gastroenterologia Y Hepatologia
|July 21, 2009
Summary
This case study highlights acute hepatitis B infection presenting with mononeuritis multiplex, a rare neurological symptom of polyarteritis nodosa (PAN). Effective treatment with antivirals and steroids led to patient recovery.
Area of Science:
- Hepatology
- Neurology
- Rheumatology
Background:
- Polyarteritis nodosa (PAN) is a systemic vasculitis with nonspecific symptoms.
- Hepatitis B infection is a known, though declining, cause of PAN, particularly its extrahepatic manifestations.
- Neurological involvement, such as mononeuritis multiplex, can be an initial presentation of PAN.
Observation:
- A 57-year-old male presented with mononeuritis multiplex and elevated transaminase levels.
- Diagnostic investigations confirmed acute hepatitis B infection and polyarteritis nodosa (PAN).
Findings:
- The patient's presentation of mononeuritis multiplex was attributed to PAN, an extrahepatic manifestation of hepatitis B.
- Treatment involved antiviral medications and corticosteroids.
Implications:
- This case underscores the importance of considering hepatitis B infection in patients with PAN, even with its decreased incidence.
- Early diagnosis and combined antiviral and steroid therapy can lead to favorable outcomes in hepatitis B-associated PAN.
- Mononeuritis multiplex serves as a critical diagnostic clue for underlying systemic diseases like PAN.
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