Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Working Memory01:24

Working Memory

Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this information.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the effect of increased dopamine signaling on cerebral blood flow in Major Depressive Disorder: a double-blind randomized placebo-controlled study.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Multiscale heterogeneity of atypical functional connectivity in autism.

Nature. Mental health·2026
Same author

Kv7.2 loss-of-function causes early hyperexcitability and network remodelling.

Brain : a journal of neurology·2026
Same author

Beyond seizures: proceedings of the ERN EpiCARE working group 18 on developmental and epileptic encephalopathies.

Epilepsy & behavior : E&B·2026
Same author

Management of ring chromosome 20 syndrome: Narrative review and consensus recommendations.

Epilepsia·2026
Same author

Social dysfunction and default mode network functional integrity in neuropsychiatric disorders: A cross-disorder replication and generalization study.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology·2026

Related Experiment Video

Updated: Jun 21, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

Working memory in children with epilepsy: an event-related potentials study.

Ivan Myatchin1, Maarten Mennes, Heidi Wouters

  • 1Department of Woman and Child, Section Paediatric Neurology, K.U.Leuven, Leuven, Belgium.

Epilepsy Research
|July 21, 2009
PubMed
Summary

Children with well-controlled idiopathic epilepsy exhibit distinct cortical activation patterns during working memory tasks compared to healthy peers. This suggests increased neural processing effort is required for similar task performance.

More Related Videos

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
11:01

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease

Published on: August 30, 2011

Related Experiment Videos

Last Updated: Jun 21, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
11:01

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease

Published on: August 30, 2011

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Pediatric Neurology

Background:

  • Idiopathic epilepsy is a common neurological condition in children.
  • Understanding cognitive processing in epilepsy is crucial for effective management.
  • Working memory tasks are sensitive to subtle neurological differences.

Purpose of the Study:

  • To investigate differences in cortical activation patterns between children with idiopathic epilepsy and non-epileptic children during a visual working memory task.
  • To utilize event-related potentials (ERPs) for quantitative analysis of neural activity.
  • To compare behavioral performance and ERPs in response to stimuli.

Main Methods:

  • Event-related potentials (ERPs) were recorded during a visual 1-back task.
  • 46 children (6-16 years) participated: 21 with well-controlled epilepsy and 25 controls.
  • Behavioral data and ERPs were analyzed quantitatively without pre-defined peak parameters.

Main Results:

  • No significant differences in behavioral performance (errors, reaction times) were observed between groups.
  • Children with epilepsy showed significantly higher ERP amplitudes over frontal and central regions.
  • This difference occurred within the 250-425 ms poststimulus window, associated with stimulus discrimination.

Conclusions:

  • Children with benign, well-controlled epilepsy display altered cortical activation during working memory tasks.
  • This suggests a greater neural processing effort is needed to achieve comparable performance levels.
  • Findings highlight potential differences in cognitive resource allocation in pediatric epilepsy.