Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Obesity

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Psychoneuroimmunology: Diabetes and Cancer

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...

Drug Dosing: Obese Patients

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Service evaluation: Accuracy of using end-tidal CO<sub>2</sub> to estimate PaCO<sub>2</sub> values in suspected traumatic brain injury patients requiring mechanical ventilation.

Journal of the Intensive Care Society·2026

Same author

'The Lightbulb Sign': why socioeconomic clues at scene matter for emergency care.

Emergency medicine journal : EMJ·2026

Same author

Competitors Unite: A Cross-Health System Collaboration to Address Community Food Insecurity.

Journal of health care for the poor and underserved·2025

Same author

Utilising a refractory ventricular fibrillation bundle to improve outcome in out of hospital cardiac arrest: A case report.

Resuscitation plus·2025

Same author

Management of persistent shockable rhythms during cardiac arrest: a national survey from the REVIVE group (REVIVE-2).

Resuscitation plus·2025

Same author

Intravenous Iron for Perioperative Anaemia in Colorectal Cancer Surgery: A Nested Cohort Analysis.

Cancers·2025

Search research articles

Related Experiment Video

Updated: Jun 21, 2026

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum

Published on: January 26, 2024

Obesity and cancer.

Rickie Brawer¹, Nancy Brisbon, James Plumb

¹Department of Family and Community Medicine, Thomas Jefferson University, 1015 Walnut - Suite 401, Philadelphia, PA 19107, USA.

|July 21, 2009

Summary

Obesity is a major preventable cause of disease and death, linked to cancer risk. Physicians play a vital role in obesity prevention and management strategies for all ages.

Area of Science:

Public Health
Epidemiology
Clinical Medicine

Background:

Obesity is the second leading preventable cause of death and disease in the US, surpassed only by tobacco use.
Modifiable factors such as weight control, diet, and physical activity significantly influence cancer risk.
Physicians are crucial in implementing multifactorial prevention and management strategies in clinical practice and advocating for broader systemic efforts.

Purpose of the Study:

To introduce the epidemiology and scope of childhood and adult obesity.
To explore the connections between obesity, cancer, and other chronic diseases.
To review obesity treatment guidelines and prevention strategies across different age groups.

Main Methods:

Review of epidemiological data on obesity prevalence.

More Related Videos

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Published on: April 23, 2021

Related Experiment Videos

Last Updated: Jun 21, 2026

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum

Published on: January 26, 2024

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Published on: April 23, 2021

Analysis of scientific literature on obesity-disease relationships and proposed mechanisms.

Synthesis of current clinical guidelines for obesity assessment and treatment.

Examination of multilevel prevention strategies and the Chronic Care Model for adult obesity management.

Main Results:

Obesity is a significant public health concern with widespread implications for chronic disease development.
Established links exist between obesity and increased risk for various cancers and other chronic conditions.
Evidence-based guidelines recommend comprehensive approaches to obesity treatment and management.
Multilevel strategies involving individual, community, and policy interventions are essential for effective prevention.

Conclusions:

Addressing the obesity epidemic requires a concerted effort from healthcare providers and public health initiatives.
Integrating obesity prevention and management into routine clinical care is paramount.
Understanding the complex relationship between obesity and chronic diseases informs targeted interventions.
Systemic changes and evidence-based guidelines are critical for reducing the burden of obesity and related diseases.