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Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4'-epimerase (GALE)
Irena Prodan-Zitnik1, Natasa Karas-Kuzelicki, Jana Lukac-Bajalo
1Department of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia. irena.prodan.zitnik@ffa.uni-lj.si
Objectives:
The aim of our study was to determine whether the activities of galactose-1-phosphate uridyltransferase and UDP-galactose-4'-epimerase are correlated, and in what way they may influence one another.
Design And Methods:
Enzyme activities were measured in red blood cells from 214 individuals.
Results:
A statistically significant (p<0.001) positive correlation was observed between GALT and GALE activities.
Conclusions:
Our results suggest that GALT and GALE activities are correlated and that GALE activity has a greater impact on GALT activity than vice versa.
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