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Updated: Jun 21, 2026

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies
Published on: April 29, 2013
Non-invasive imaging of nerve regeneration
1Department of Neurology, University of Texas Health Sciences Centre, Houston, 6431 Fannin Street, MSE 454, Houston, TX 77030, USA. Kazim.Sheikh@uth.tmc.edu
Abstract:
The need for non-invasive imaging of peripheral nerves that can reliably assess extent of nerve fiber degeneration and regeneration is increasingly realized. Availability of such a technology has several immediate clinical and preclinical applications. Diffusion tensor imaging (DTI) is an emerging magnetic resonance based technology that is particularly suited for imaging nerve fiber tracts. This review highlights immediate clinical and preclinical uses of non-invasive imaging of peripheral nerve regeneration and DTI as a potential technology that can fulfill these clinical and research needs.

