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Related Experiment Video

Updated: Jun 21, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Published on: April 27, 2014

Bladder sensation measures and overactive bladder.

David E Rapp¹, Nancy J Neil, Fred E Govier

¹Continence Center at Virginia Mason Medical Center, Seattle, Washington 98111, USA. derapp@yahoo.com

The Journal of Urology

|July 21, 2009

Summary

This summary is machine-generated.

Bladder sensation questionnaires effectively identify sensory dysfunction in overactive bladder patients. Urodynamic measures correlate with these scores, offering an objective assessment method.

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Detrusor Underactivity Model in Rats by Conus Medullaris Transection

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Last Updated: Jun 21, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Published on: April 27, 2014

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Area of Science:

Urology
Neuroscience
Medical Devices

Background:

Overactive bladder (OAB) significantly impacts quality of life.
Assessing bladder sensation is crucial for understanding OAB pathophysiology.
Current methods for evaluating bladder sensation have limitations.

Purpose of the Study:

To determine if subjective and objective bladder sensation instruments can identify sensory dysfunction in OAB patients.
To explore the correlation between validated questionnaires and urodynamic parameters.
To investigate novel urodynamic derivatives as potential measures of bladder sensation.

Main Methods:

Prospective study of 70 OAB patients.
Utilized urodynamics and validated questionnaires: Urgency Perception Score (UPS), Urogenital Distress Inventory (UDI), and Incontinence Impact Questionnaire (IIQ).
Assessed correlations between sensory scores and urodynamic variables, including first sensation ratio and bladder urgency velocity.

Main Results:

Moderate correlations found between UPS, UDI, and IIQ scores.
A weak negative correlation was observed between UPS and bladder capacity.
Novel urodynamic derivatives (first sensation ratio, bladder urgency velocity) significantly correlated with UPS.

Conclusions:

Bladder sensation questionnaires are valuable tools for identifying sensory dysfunction in OAB.
Questionnaires provide data beyond generalized symptom assessments.
Urodynamic variables show potential as objective measures for assessing bladder sensory dysfunction.