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Related Experiment Video

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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

At Sidibe, I Cisse, As Diarra

    Le Mali Medical
    |July 21, 2009
    PubMed
    Summary
    This summary is machine-generated.

    Sexual ambiguities, affecting 0.54% of patients, present diverse clinical features in internal medicine. This study highlights common presentations like external genital anomalies and delayed puberty in phenotypically feminine individuals.

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    Area of Science:

    • Endocrinology
    • Reproductive Medicine
    • Pediatrics

    Background:

    • Sexual ambiguities encompass a range of conditions stemming from congenital or hormonal factors.
    • Understanding the clinical spectrum is crucial for timely diagnosis and management in internal medicine settings.

    Purpose of the Study:

    • To describe the clinical manifestations of sexual ambiguities encountered in internal medicine.
    • To analyze the prevalence and specific features of sexual ambiguity cases in a tertiary hospital in Mali.

    Main Methods:

    • A combined retrospective (1995-2000) and prospective (2001-2002) study design.
    • Inclusion of 12 patients diagnosed with sexual ambiguities out of 2223 total consultations (0.54% prevalence).
    • Detailed clinical assessment of phenotypically feminine and masculine patients.

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    High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
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    High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

    Published on: November 15, 2013

    Main Results:

    • Ten patients were phenotypically feminine, presenting with external genital anomalies (3/10), sparse pubic/axillary hair (5/10), delayed puberty (4/10), primary amenorrhea (6/10), hypoplastic mammary glands (7/10), and inguinal masses (3/10).
    • Two patients were phenotypically masculine, one with bilateral gynecomastia, tall stature (2.04m), and sparse hair, the other with external genital anomalies.
    • Average patient age was 14.3 ± 8.9 years.

    Conclusions:

    • Sexual ambiguities present with varied clinical signs, requiring thorough evaluation in internal medicine.
    • The study underscores the importance of recognizing diverse presentations, particularly in phenotypically feminine individuals, to guide appropriate diagnostic and therapeutic interventions.