Related Experiment Video

Updated: Jun 21, 2026

Using an α-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking
11:57

Using an α-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking

Published on: March 28, 2014

GABA(A) receptor membrane trafficking regulates spine maturity

Tija C Jacob1, Qin Wan, Mansi Vithlani

  • 1Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02030, USA.

Proceedings of the National Academy of Sciences of the United States of America
|July 21, 2009
PubMed
Summary

Altering GABA(A) receptor (GABA(A)R) trafficking enhances inhibitory synapses and transmission by reducing receptor endocytosis. This modulation impacts spine maturity and synaptic plasticity.

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