Multivisceral resection for colon carcinoma.

Area of Science:

• Oncology
• Surgical Oncology
• Gastrointestinal Surgery

Background:

• Complete resection is the goal of curative surgery for colon carcinoma.
• Locally advanced colon carcinomas with organ adhesion often necessitate multivisceral resections.
• The study evaluates the efficacy and influencing factors of multivisceral resection in primary colon carcinomas.

Purpose of the Study:

• To investigate the value of multivisceral resection in primary colon carcinomas.
• To identify factors influencing the success of multivisceral resection.
• To assess outcomes including complications, recurrence, and survival.

Main Methods:

• Analysis of prospectively collected data from 174 patients undergoing multivisceral resection for colon carcinoma (1978-2002).
• Multivisceral resection defined as resection of the colon plus at least one additional organ.
• Evaluation of postoperative complications, locoregional recurrence, distant metastases, and cancer-related survival over a five-year follow-up.

Main Results:

• R0 resection (no residual tumor) was achieved in 93.1% of cases.
• Commonly resected organs included small intestine (31.6%), urinary bladder (27.0%), and abdominal wall (15.5%).
• Five-year cancer-related survival was 80.7% for R0 resections; no R1/R2 survivors.
• Postoperative complications occurred in 25.8%, with a 6.9% mortality rate.

Conclusions:

• Multivisceral resection is justified for locally advanced colon carcinomas due to high R0 resection rates.
• Experienced surgeons are vital for reducing locoregional recurrence.
• Successful R0 resection is critical for long-term cancer-related survival.