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Updated: Jun 21, 2026

The Ex vivo Preparation of Spinal Cord Slice for the Whole-Cell Patch-Clamp Recording in Motor Neurons During Spinal Cord Stimulation
Published on: September 8, 2023
The characteristics of no-go potentials with intraepidermal stimulation
Hiroki Nakata1, Kiwako Sakamoto, Koji Inui
1Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan. nakata@nips.ac.jp
Abstract:
The objective of this study was to investigate whether no-go potentials during go/no-go tasks were observed after painful stimulation using intraepidermal electrical stimulation. Event-related potentials were recorded by stimulating the medial or lateral side of the left-hand dorsum. Peak amplitudes of N2 and P3 were significantly larger in no-go trials than in go trials at frontocentral electrodes during go/no-go task, but the differences were not found during rest control and choice reaction time tasks. These characteristics of no-go-related potentials were very similar to event-related potential waveforms during visual, auditory, and somatosensory go/no-go tasks. We suggest that cortical activities relating to response inhibitory processing are not dependent on the sensory modality used.
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