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Related Concept Videos

Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

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Related Experiment Video

Updated: Jun 21, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Pulmonary eosinophilia.

Luiz Eduardo Mendes Campos1, Luiz Fernando Ferreira Pereira

  • 1Residency Program in Pulmonology and Respiratory Outpatient Clinic. Júlia Kubitschek Hospital, Fundação Hospitalar do Estado de Minas Gerais - FHEMIG, Hospital Foundation of the State of Minas Gerais - Belo Horizonte, Brazil. lemendescampos@yahoo.com.br

Jornal Brasileiro De Pneumologia : Publicacao Oficial Da Sociedade Brasileira De Pneumologia E Tisilogia
|July 21, 2009
PubMed
Summary
This summary is machine-generated.

Pulmonary eosinophilia is a diverse lung condition marked by eosinophils in lung tissue or fluid. Recognizing its varied causes and presentations is key for accurate diagnosis and effective treatment.

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Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
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Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

Published on: May 30, 2020

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Last Updated: Jun 21, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
08:44

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

Published on: May 30, 2020

Area of Science:

  • Pulmonology
  • Immunology
  • Pathology

Background:

  • Pulmonary eosinophilia encompasses a range of diseases characterized by eosinophilic infiltration in lung tissues or lavage fluid.
  • Eosinophilia is a critical diagnostic and therapeutic marker, despite the presence of other inflammatory cells.

Purpose of the Study:

  • To review the heterogeneous group of pulmonary eosinophilia diseases.
  • To highlight the clinical, radiological, and etiological aspects of pulmonary eosinophilia.

Main Methods:

  • Review of clinical presentations, radiological findings, and etiologies of pulmonary eosinophilia.
  • Categorization of diseases including simple pulmonary eosinophilia, chronic eosinophilic pneumonia, acute eosinophilic pneumonia, allergic bronchopulmonary aspergillosis, and systemic associations.

Main Results:

  • Clinical and radiological features vary, with distinct patterns for chronic eosinophilic pneumonia, acute eosinophilic pneumonia, and allergic bronchopulmonary aspergillosis.
  • Etiologies are diverse, including idiopathic causes, infections (fungal, mycobacterial), drugs, toxins, irradiation, and associations with systemic diseases, connective tissue diseases, and neoplasms.
  • Associated conditions like asthma, Churg-Strauss syndrome, and hypereosinophilic syndrome are frequently observed, impacting organs such as skin, heart, and nervous system.

Conclusions:

  • Pulmonary eosinophilia is a complex syndrome with varied presentations and causes.
  • Accurate diagnosis relies on recognizing specific clinical and radiological patterns and identifying underlying etiologies.
  • Management strategies are guided by the specific type and cause of pulmonary eosinophilia.