Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum sickness, a systemic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: Time-resolved dosimetry for validation of 4D dose calculation in PBS proton therapy (2020<i>Phys. Med. Biol.</i>65 125015).

Physics in medicine and biology·2025
Same author

[Virtual training of practical competences in sonography].

HNO·2024
Same author

[Is the use of virtual reality in otorhinolaryngology teaching automatically positively rated by students? : A questionnaire-based evaluation among students].

HNO·2024
Same author

[Feasibility of clinical examination scenarios under pandemic conditions].

HNO·2024
Same author

[Salivary gland cancer].

HNO·2023
Same author

[Frozen section biopsy for tumors of the submandibular triangle].

HNO·2022
Same journal

[Complications of acute otitis media].

HNO·2026
Same journal

HNO·2026
Same journal

[Facial fillers: evidence base, anatomical principles, materials, risks, techniques, and future perspectives].

HNO·2026
Same journal

Prevention in otology-the key to lifelong hearing health.

HNO·2026
Same journal

[Bilateral low-frequency hearing loss and tinnitus following spinal anesthesia during a cesarean section].

HNO·2026
Same journal

[Chronic mesotympanic otitis media with an atypical course : A rare differential diagnosis].

HNO·2026
See all related articles

Related Experiment Video

Updated: Jun 21, 2026

Modified Radical Neck Dissection for Cervical Metastasis
06:05

Modified Radical Neck Dissection for Cervical Metastasis

Published on: February 20, 2026

[Complication after subacute cervical lymphadenitis].

A Knopf1, E Q Scherer

  • 1Hals-Nasen-Ohren-Klinik und Poliklinik, Klinikum rechts der Isar der technischen Universität München, Ismaninger Strasse 22, 81675, München. andreas.knopf1@gmx.net

HNO
|July 21, 2009
PubMed
Summary
This summary is machine-generated.

A patient with factor V Leiden mutation developed neck swelling and internal jugular vein thrombosis. This case highlights the thrombotic risks associated with this genetic predisposition and lymphadenitis.

More Related Videos

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain
08:03

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

Surgical Protocols for Deep Cervical Lymphovenous Anastomosis in a Rat Model: Lymph Node and Lymphatic Vessel Anastomoses
07:37

Surgical Protocols for Deep Cervical Lymphovenous Anastomosis in a Rat Model: Lymph Node and Lymphatic Vessel Anastomoses

Published on: November 14, 2025

Related Experiment Videos

Last Updated: Jun 21, 2026

Modified Radical Neck Dissection for Cervical Metastasis
06:05

Modified Radical Neck Dissection for Cervical Metastasis

Published on: February 20, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain
08:03

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

Surgical Protocols for Deep Cervical Lymphovenous Anastomosis in a Rat Model: Lymph Node and Lymphatic Vessel Anastomoses
07:37

Surgical Protocols for Deep Cervical Lymphovenous Anastomosis in a Rat Model: Lymph Node and Lymphatic Vessel Anastomoses

Published on: November 14, 2025

Area of Science:

  • Vascular Medicine
  • Hematology
  • Infectious Disease

Background:

  • Factor V Leiden mutation is a common inherited thrombophilia.
  • Activated Protein C (APC) resistance is a key mechanism in factor V Leiden mutation.
  • Subacute lymphadenitis can present with cervical swelling and systemic inflammation.

Observation:

  • A 56-year-old female presented with odynophagia and painful left neck swelling.
  • Clinical examination revealed cervical redness, swelling, and tenderness.
  • Laboratory tests showed leukocytosis, elevated C-reactive protein (CRP), and fibrinogen levels.

Findings:

  • Sonography and CT scans identified enlarged lymph nodes and internal jugular vein thrombosis.
  • The patient was a heterozygote carrier of the factor V Leiden mutation.
  • Subacute lymphadenitis was identified as a contributing factor to the thrombosis.

Implications:

  • This case underscores the potential for venous thromboembolism in individuals with factor V Leiden mutation, especially when complicated by infection.
  • Early diagnosis and anticoagulation are crucial for managing such thrombotic events.
  • Understanding the interplay between genetic predisposition and inflammatory conditions is vital for patient management.