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Updated: Jun 21, 2026
Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents
Published on: August 14, 2018
Influence of electromagnetic fields on bone fracture in rats: role of CAPE
Ekrem Cicek1, Osman Gokalp, Remzi Varol
1Department of Physics, Faculty of Arts and Science, Mehmet Akif Ersoy University, Burdur Turkey. ekrcicek@yahoo.com
Objective:
To study the effects of radiation emitted by mobile phones on bone strength and caffeic acid phenethyl ester (CAPE) on the changes induced by radiation.
Methods:
Forty-eight Sprague-Dawley rats were divided into five groups. Rats in the control group (first group) were left within the experimental setup for 30 min/day for 28 days without radiation exposure. Nine hundred MHz radiation group was broke down into 2 subgroups (group 1/2). Both subgroups were exposed to radiation for 28 days (30 min/day). The next group was also divided into 2 subgroups (group 3/4). Each was exposed to 1800 MHz of radiation for 28 days (30 min/day). The third and fifth groups were also treated with CAPE for 28 days. Treatment groups received ip caffeic acid phenethyl ester (10 micromol/kg per day) before radiation session. Bone fracture was analyzed.
Results:
Breaking force, bending strength, and total fracture energy decreased in the irradiated groups but increased in the treatment groups.
Conclusion:
Radiation and CAPE can significantly improve bone.
