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Effects of cow's milk on reproduction in ICR male mice
Yu-Xia Ma1, Naoyuki Ebine, Kazuo Aoki
1Department of Human Environmental and Social Medicine, Division of Preventive Medicine, Faculty of Medicine, Oita University, 1-1 Idaigaoka Hasama-machi, Oita 879-5593, Japan. mayuxia@hebmu.edu.cn
Objective:
To study the effects of Cow's milk on the reproduction in male mice.
Methods:
Twenty-four male mice were divided randomly into two groups: milk group (M) and control group (C). Each mouse was given 10 mL milk per day from 4 to 16 weeks in the group M. At the age of 17 weeks, all the mice were sacrificed.
Results:
Serum testosterone was decreased in the group M (P=0.037). No significant difference was found in weight of testes, seminal vesicle or adrenal gland of mice between the groups C and M. However, the weight of seminal vesicle decreased when expressed in g/100 g body weight in the group M. Epididymal sperm concentration, motility, morphology, and sperm head number were not affected by milk.
Conclusion:
Cow's milk has adverse effects on the reproductive system in ICR male mice. Further studies are needed to clarify the specific effects of milk on reproductive health.
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