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Published on: October 4, 2019
[Apigenin glycosides from Euphorbia humifusa wild]
Ying Tian1, Xi-qiao Liu, Jun-xing Dong
1Department of Pharmaceutical Chemistry, Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China.
Abstract:
The investigation on the herbal of Euphorbia humifusa Wild. was carried out in order to find its anti-HBV constituents. The isolation and purification were performed by chromatography such as Sephadex LH-20, MCI GEL CHP 20P, etc. Based on the spectral analysis, five apigenin glycosides were identified as apigenin-7-O-(6"-O-galloyl)-beta-D-glucopyranoside (1), apigenin-7-O-beta-D-apiofuranosyl (1-->2)-beta-D-glucopyranoside (2), apigenin-7-O-beta-D-lutinoside (3), apigenin-7-O-beta-D-glucopyranside (4) and apigenin (5). Among them, compound 1 is a new compound, compound 2 and 3 were isolated from this plant for the first time.