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Using EQ-5D in children with asthma, rheumatic disorders, diabetes, and speech/language and/or hearing disorders
Daniëlle C M Willems1, Manuela A Joore, Fred H M Nieman
1Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, The Netherlands. danielle.willems@epid.unimaas.nl
Insights
The EQ-5D child version shows good practicality and reliability for children with chronic conditions, especially those with stable health. However, supplementary disease-specific tools are recommended for comprehensive assessment.
Area of Science:
- Pediatric Health Outcomes
- Health Economics and Outcomes Research
- Quality of Life Measurement
Background:
- Assessing health-related quality of life (HRQoL) in children with chronic conditions is crucial.
- The EQ-5D child version is a multi-attribute utility instrument designed for this purpose.
- Evaluating its psychometric properties in pediatric populations is essential for valid application.
Purpose of the Study:
- To explore the psychometric properties of the EQ-5D child version.
- To assess its practicality, convergent validity, discriminant power, and test-retest reliability.
- To determine its suitability for children aged 7-18 with various chronic conditions.
Main Methods:
- A convenience sample of 182 children (aged 7-18) with asthma, rheumatic disorders, diabetes, or speech/language/hearing disorders participated.
- The EQ-5D child version was compared with the TACQOL generic questionnaire.
- Practicality, convergent validity, discriminant power, and 2-week test-retest reliability were evaluated.
Main Results:
- The EQ-5D child version demonstrated good practicality.
- Low to moderate correlations were observed between EQ-5D utilities/VAS scores and TACQOL scales.
- Discriminant power was generally low but higher in children with rheumatic disorders; reliability was moderate to high for those with stable health.
Conclusions:
- The EQ-5D child version appears suitable for assessing HRQoL in children, particularly those with chronic physical conditions and stable health.
- Its reliability is promising for children with stable health status.
- Complementary use of disease-specific questionnaires is advised for a more thorough evaluation.
Objectives:
This study explores several variables of the EQ-5D child version, a multi-attribute utility instrument, in children with chronic conditions.
Methods:
A convenience sample was selected from hospital outpatient records and school records. The sample included children aged 7-18 years with the following chronic conditions: asthma, rheumatic disorders, diabetes, and speech/language and/or hearing disorders. The practicality, convergent validity, and discriminant power were compared with a generic quality of life questionnaire for children (TACQOL) and the 2-week test-retest reliability was assessed.
Results:
A total of 182 children or their parents completed the first questionnaire and 161 children/parents completed both questionnaires. The practicality of the EQ-5D was good. Low to moderate correlations were found between the utilities and VAS scores and the TACQOL scales. The discriminant power of the EQ-5D items was low overall and was greater for children with a rheumatic disorder than for children with the other conditions. In the subset of children who experienced no health change between the test and the retest, the reliability of the EQ-5D was moderate to high.
Conclusions:
The EQ-5D seems suitable for children, although the use of an additional disease-specific questionnaire is still recommended. The EQ-5D seems the most suitable for children with a chronic physical condition and appears to be reliable for children with a stable health status.
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