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Updated: Jun 21, 2026
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A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
Atherosclerotic renal artery stenosis: current therapy and future developments
Ranjith Shetty1, Mitesh S Amin, Ion S Jovin
1Cardiovascular Division, Department of Internal Medicine, Virginia Commonwealth University Health System/Medical College of Virginia, Richmond, VA, USA.
American Heart Journal
|July 22, 2009
Summary
Atherosclerotic renal artery stenosis (ARAS) affects millions, often linked to hypertension and kidney dysfunction. Renal artery stenting offers high success for select patients, improving outcomes.
Area of Science:
- Cardiology
- Nephrology
- Vascular Medicine
Background:
- Atherosclerotic renal artery stenosis (ARAS) impacts millions in the US, with potentially underestimated prevalence.
- ARAS is increasingly recognized, particularly in patients with existing cardiovascular disease.
- Associated conditions include hypertension, renal dysfunction, and pulmonary edema.
Purpose of the Study:
- To review the clinical diagnosis of ARAS.
- To discuss current treatment options for ARAS.
- To explore future directions in ARAS management.
Main Methods:
- Review of existing literature on atherosclerotic renal artery stenosis.
- Analysis of diagnostic criteria and clinical presentation.
- Evaluation of revascularization techniques, primarily renal artery stenting.
- Assessment of patient selection for interventions.
Main Results:
- Renal artery stenting demonstrates high patency rates and low complication rates.
- Identifying patients who will benefit most from revascularization is crucial.
- ARAS is linked to significant comorbidities, highlighting the need for comprehensive management.
Conclusions:
- Effective management of ARAS requires accurate diagnosis and patient selection for interventions like stenting.
- Further research is needed to optimize treatment strategies and improve long-term outcomes.
- Understanding the prevalence and impact of ARAS is essential for public health initiatives.
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