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Updated: Jun 21, 2026

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
Published on: April 1, 2019
Brown fat: atypical locations and appearances encountered in PET/CT
Sanjay Paidisetty1, Todd M Blodgett
1Department of Radiology, Hillman Cancer Center, University of Pittsburgh, 5115 Centre Ave., Pittsburgh, PA 15232, USA.
Objective:
The purpose of this article is to review the physiology and describe the typical and atypical presentations of brown fat on (18)F-FDG PET.
Conclusion:
The presence of brown fat on FDG PET has the potential to lead to misinterpretation and unneeded invasive tests, which can be avoided by using measures such as ensuring the patient is warm, reducing FDG uptake in brown fat before the procedure, and correlating PET uptake to a specific anatomic location with PET/CT fusion imaging.
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