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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

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Related Experiment Video

Updated: Jun 21, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Donor selection and management.

Gregory I Snell1, Glen P Westall

  • 1Lung Transplant Service, Alfred Hospital and Monash University, Melbourne, Victoria, Australia. g.snell@alfred.org.au

Current Opinion in Organ Transplantation
|July 22, 2009
PubMed
Summary
This summary is machine-generated.

Expanding donor lung utilization through advanced selection and management strategies can significantly increase transplant rates. This approach aims to overcome donor organ scarcity and improve outcomes for patients awaiting lung transplants.

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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

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Related Experiment Videos

Last Updated: Jun 21, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
07:08

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Area of Science:

  • Pulmonology
  • Transplant Surgery
  • Organ Donation Science

Background:

  • Lung transplantation is limited by a critical shortage of suitable donor organs.
  • Current donor lung utilization rates remain low, below 20%, leading to prolonged waiting times and increased mortality.

Purpose of the Study:

  • To review recent advancements in the selection, assessment, and management of potential lung donors.
  • To explore strategies for increasing donor lung utilization rates to over 50%.

Main Methods:

  • Review of current literature on lung donor criteria and management.
  • Analysis of novel approaches including donation after cardiac death, cut-down lungs, and expanded criteria donors.

Main Results:

  • Historical donor acceptability criteria have restricted organ availability.
  • Utilizing donation after cardiac death, cut-down, and expanded criteria lungs increases donor lung availability.
  • Emerging diagnostic tools show promise for predicting post-transplant lung function.

Conclusions:

  • Aggressive donor management and consideration of expanded donor criteria are crucial for maximizing organ donation.
  • Long-term studies are necessary to validate these approaches and ensure favorable transplant outcomes.