[The peculiarities of epilepsy in the menopause]

Twenty seven cases with the combination of epilepsy and menopause are presented. The menopause proved to be a critical period for epilepsy manifestation: in 44.4% women with epilepsy the disease onset was observed at the peri- and post-menopause period. The course of epilepsy during this period was less severe: the frequency of seizures increased in 7.4% and decreased in 33.3%, no changes in the frequency of seizures were observed in 59.3%. The severity of menopause syndrome was not correlated with duration and severity of epilepsy, 81.4% of patients had the mild severity of this syndrome. The reduction of bone density was found in most of women (85.2%). It implies that all patients with epilepsy and menopause should receive a prophylactic treatment to prevent osteopenia. About 18.6% of patients required the hormone replacement therapy but only 7.4% received it due to adverse effects.