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Updated: Jun 21, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
The feasibility and safety of endoscopic resection for benign hypopharyngeal tumors
Beom Jae Lee1, Jong-Jae Park, Moon Kyung Joo
1Division of Gastroenterology, Department of Internal Medicine, Korea Univerisity Guro Hospital, Seoul, Korea.
Background/Aims:
For hypopharyngeal tumors, surgical therapy under general anesthesia is the mainstay of treatment; however, the endoscopic treatment of benign hypopharyngeal tumors has not been fully evaluated for its feasibility and safety. We determined the technical feasibility and safety of endoscopic treatment for benign hypopharyngeal tumors.
Methodology:
A total of 22 patients (15 men, 7 women) with benign hypopharyngeal tumors underwent endoscopic resection. All tumors were treated using one of two endoscopic mucosal resection (EMR) techniques: the injection and cut method for the polypoid lesions (6 cases) or EMR using a cap (EMR-C) for the flat or protruding lesions with wide bases (16 cases).
Results:
In all 22 patients, the most common findings detected during routine GI endoscopy were lymphoepithelial cysts (11 cases) followed by papillomas (5 cases). All benign hypopharyngeal tumors were successfully removed by endoscopic resection without sedation. There were no major procedure-induced complications. Minor complications occurred in 3 patients and included minimal bleeding (n=1), pain (n=1) and low-grade fever (n=1).
Conclusions:
As a treatment modality for benign hypopharyngeal tumors, endoscopic resection is a simple, less invasive, safe, and likely cost-effective method. Endoscopic resection should be considered an alternative to surgical therapy in appropriately selected patients.

