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Updated: Jun 21, 2026

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Localization of Plasma Membrane and Intracellular Neuronal Nicotinic Acetylcholine Receptors Using Quantitative Imaging in Mammalian Cells
Published on: December 19, 2025
[Neuronal nicotinic receptors: structure and function in different types of cells]
Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
|July 23, 2009
Summary
This review covers nicotinic acetylcholine receptors (nAChRs) in various tissues, including immune cells. It details their subunit composition, functions, and roles in both excitable and non-excitable systems.
Area of Science:
- Neuroscience and Pharmacology
- Molecular and Cellular Biology
Context:
- Nicotinic acetylcholine receptors (nAChRs) are crucial signaling molecules.
- Their presence extends beyond the nervous system to non-excitable tissues and immune cells.
Purpose:
- To review current literature on nAChR subunit composition and function.
- To highlight the expression and roles of nAChRs in diverse cell types, particularly immune cells.
Summary:
- Examines nAChR structure and function in excitable tissues like the brain and autonomic ganglia.
- Details nAChR involvement in non-excitable tissues including respiratory epithelium, vascular endothelium, skin, and blood.
- Focuses on the expression patterns and functional significance of nAChRs within immune cell populations.
Impact:
- Provides a comprehensive overview of nAChR distribution and function across multiple biological systems.
- Underscores the potential of nAChRs as therapeutic targets in inflammatory and autoimmune conditions.
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